Effect of EDTA Chelation Therapy on Aortic Calcium in Rabbits on Atherogenic Diets; Quantitative and Histochemical Studies

Image 1

The red stained area represents Calcium deposits in the arteries

Image 2

The red stained area represents Calcium deposits in the arteries

 group of rabbits were sub-divided into two subgroups, the first being placed on a standard laboratory diet while the second was placed on a high cholesterol containing atherogenic diet.  The animals were either infused with EDTA, saline, or nothing (in the controls) followed by sacrificing and the aortas were examined for calcium both microscopically, using calcium stains, and quantitatively.  Results indicated significantly less calcium in the aortas of the EDTA infused animals when compared to both controls and saline infused animals.


Robert L. Kaman, Ph.D., Charles J. Rudolph, Jr., D.O., Ph.D. Edward W. McDonagh, D.O., A.C.G.P., Foster M. Walker, Ph.D.   


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